ABSTRACT
The paper develops the concept of a timescape of a city based on empirical analysis of geospatial big data. We understand the timescape as the temporal shape of a city, which reflects temporal dynamics of a city structure and rhythms based on aggregated time-space behaviour of individuals. The paper uses the concepts of rhythmanalysis and spatial interactions as theoretical basis. We analyse two data types: mobile phone location data and taxi trajectory data, and the city of Prague is taken as the example. The data capture the population mobility peak before the Covid-19 pandemic has burst out. We examine both the temporal (weekly and daily rhythms) and spatial (intra urban and 'extra' urban flows) hierarchies of the city time-space. We have confirmed the existence of distinct differences between workdays and weekend days. It has also been shown that the mobility based on taxi trajectories has specific temporal distribution. Based on 'extra' urban flows, rhythms and thus on the present population of the city we have identified two hierarchically different time waves, long (weekly) and short (daily), when the latter has opposite amplitude and span during workdays and during weekend days.
ABSTRACT
Avian infectious bronchitis (IB) is an economically important, highly contagious, acute disease of Chickens caused by a single-stranded positive RNA Virus that belongs to the Coronaviridae family. The Virus can replicate in the oviduct and cause permanent damage in young hens resulting in the false layer occurrence. In laying hens, infectious bronchitis Virus (IBV) infections can cause a severe decline in egg production and a number of effects on egg quality and reduced hatchability. The most effective means of controlling IB in poultry is vaccination. In the areas with increased pressure of circulating field challenge Virus, live attenuated vaccines are also used during the laying period with the intention of keeping local protection of the respiratory tract at a high level. The vaccine strain IB V-173/11 contained in Avishield IB GI-13 vaccine is a strain that genetically (S1 gene) belongs to GI-13 lineage and antigenically to 793B IBV serotype. Viral infections of this serotype occur frequently in Europe and therefore most vaccination programs in broilers, layers and breeders along a live IBV vaccine of the Massachusetts serotype also include a live vaccine of the 793B serotype, GI-I3 lineage. In this paper, results of a safety evaluation of live attenuated IB vaccine strain V-173/11, when administered by spray method in a ten-fold maximum dose repeated by one maximum dose in 28-week-old specific pathogen free (SPF) layer Chickens are presented. As a control, non-vaccinated SPF layer chickens were included in the study. The vaccine is considered to be safe when used in laying period because no vaccinated chicken showed abnormal local or systemic reactions or signs of IB related disease, no chicken died from the causes attributable to the vaccine, egg quality was not altered, and there was no statistically significant difference in. egg production between the vaccinated and non-vaccinated group.